Article

Building prosperity by advancing medical devices

Frédéric Leblond — Co-founder, Reveal Surgical and Exclaro
Institution(s)
École Polytechnique de Montréal
Province(s)
Quebec

Detecting cancer tissue in real time

Receiving a brain cancer diagnosis is overwhelming and can evoke profound fear and uncertainty. This anxiety is compounded by the prospect of surgery, which carries significant risks and potential consequences. 

Surgeons face the complex challenge of distinguishing between healthy and cancerous tissue during surgery, which can lead to incomplete tumour removal or inadvertent damage to healthy areas. Such outcomes may result in higher recurrence rates and a greater need for repeat surgeries, placing additional strain on an already overburdened healthcare system

“Giving surgeons the opportunity to identify cancerous tissue with unprecedented precision is more than just a medical breakthrough,” says Frédéric Leblond, a physicist with a passion for improving cancer treatment. “It’s an economic catalyst.” 

Leblond started Reveal Surgical in 2015 with Chief of Neurosurgery at McGill University Health Centre, Kevin Petrecca. Together, they conceived the Sentry technology, which uses Raman light scattering to identify cancerous tissue during surgery using a hand-held probe. When laser light hits tissue, it scatters and creates a unique “fingerprint” for each type of tissue, then Sentry's AI engine analyzes this fingerprint in real time, helping surgeons quickly determine if the tissue is cancerous or healthy.

Our system delivers more cost-effective surgeries and frees up critical resources in healthcare systems, and most important, better patient outcomes.

Yesterday’s investments drive results today 

He drew inspiration for this technology while researching innovative ways to differentiate healthy and cancerous tissues at Polytechnique Montréal. Leblond emphasizes that the support from Canadian funding programs, especially the CFI, was pivotal in his journey from research to developing cutting-edge cancer surgery solutions. “CFI funding for our equipment laid the foundation for our success,” says Leblond. 

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Building prosperity for Canada
  • Over $8 million of capital raised
  • Winner of the 2017 Quebec Science Discovery of the Year Award for the Sentry system
  • 20+ people involved with the companies in Montréal
  • Over 14,000 fingerprints from five cancer types collected and inventoried

Partnerships extend internationally 

Reveal Surgical has formed key partnerships with major healthcare institutions and medical device manufacturers, including McGill University Health Centre and the Icahn School of Medicine at Mount Sinai in New York City. “Our work in advancing medical devices for cancer surgery is not only saving lives but also driving economic development and reinforcing Quebec’s efforts to become a global hub for medical innovation,” says Leblond, speaking of Quebec’s agenda to become one of the top five North American life sciences clusters by 2027. 

Exponential uses for other medical applications 

Reveal is also exploring the use of Sentry technology for prostate cancer, lung cancer and possible applications for breast tissue analysis. Leblond co-founded the company Exclaro that was also spearheaded by CFI funding. The new company is developing a device that relies on technology similar to Sentry that that will lead to diagnostic tests in oncology to allow early cancer screening and disease recurrence monitoring to optimize treatment planning.

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